Having lost season's first Derby d'Italia 1-2 at home against Juventus before the international break, Inter Milan know they can't allow the defending champions to create a gap at the top of the table.
Antonio Conte's men could find themselves further behind the pace by the time they kick the ball at Mapei Stadium if Juve win their home game against Bologna.
With no disrespect to Sassuolo, these are the kind of games Inter must win to sustain a title challenge with Juventus. While Atalanta's convincing 3-0 win over Lazio means, Inter are 3rd on the table.
The hosts though will hope to end a two-game skid in front of the fans and pull themselves clear away from the dreaded relegation zone.
The Serie A match will be played between Sassuolo and Inter Milan at Stadio Città del Tricolore, Reggio Emilia, Italy. The ground has a capacity of 23,717
The game will start at 04:00 PM (IST), on Sunday, October 20.
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Recent form (Last six matches)
Sassuolo – L W L W L L
Inter Milan – D W W W L L
Sassuolo Team News:
Brazilian left-back Rogerio, and Italian goalkeeper Gianluca Pegolo are both listed as out for Sassuolo.
In addition, on-loan Napoli defender Vlad Chiriches is a doubt for the match having returned from international duty with Romania with an injury.
Expect changes from the hosts:
Sassuolo's last league game before the international break was postponed following the death of their resident Giorgio Squinzi. With three weeks between their last game and this match, manager Roberto De Zerbi is expected to rin in a few changes.
One may come at the back if Chiriches fails to recover from the injury. If that remains the case, expect Gian Marco Ferrari and Marlon Santos to partner at the back. While wing-backs Toliso and Pelijan are fit and should reprise their roles in the playing 11.
Mehdi Bourabia and Hamed Junior Traore battle for a place in the midfield, while Jeremie Boga looks to start ahead of Gregoire Defre.
Sassuolo Probable XI:
Consigli (GK), Peluso, Ferrari, Santos, Toljan, Duncan, Obiang, Traore, Berardi, Defrel / Boga, Caputo
Inter Milan FC Team News:
Inter Milan midfielder Stefano Sensi, who suffered an injury to his adductor muscles during the clash against Juventus, felt pain in his right thigh during training. He is ruled out from this game.
Alexis Sanchez had surgery on his right ankle and will be out of action for the next few weeks.
Italian full-back Danilo D’Ambrosio picked up an injury while representing Italy in the European qualifiers. The 31-year-old defender has fractured the proximal phalanx bone in the fourth toe of his right foot.
Inter Milan – Likely changes!
Inter Milan have a huge Champions League game coming up in the midweek against Borussia Dortmund, so Antonio Conte may make a few changes to keep his squad as fresh as possible.
Lautaro Martinez was involved in Argentina's games and maybe given a rest here. In that case, Matteo Politano is expected to partner Romelu Lukaku in the attack.
Danilo D'Ambrosio will miss the game through injury with Antonio Candreva coming into the playing 11 to replace him.
Diego Godin should get a rest here with Alessandro Bastoni replacing the former Atletico Madrid star at the back.
Roberto Gagliardini is expected to come in for Stefano Sensi in midfield.
Inter Milan Probable XI:
Handanovic (GK), Bastoni, Vrij, Skriniar, Asamoah, Gagliardini, Brozovic, Barella, Candreva, Politano, Lukaku
Likely to score:
Captain and Vice-Captain Selection:
Romelu Lukaku: Has scored three goals.
Domenico Berardi: Leading the team with five strikes in the league.
Francesco Caputo: Has scored three times in the league.
Nicolo Barella: Inter's most in-form player this season. Can make a difference from the midfield.
INT vs SAS Dream11 potential winner:
Inter Milan will have too much for Sassuolo in this match.