Lionel Messi is expected to take a more central position in Suarez’s absence. Coutinho and Dembele will be on either side.
Midfielder Rafinha is another who needs surgery because of a torn ligament in his right knee and is expected to return to action early next season.
Reserve goalkeeper Jasper Cillessen, midfielder Arthur Melo also among others on the sidelines.
Ivan Rakitic and Coutinho have regained fitness but it remains to be seen whether they start or not.
Ter Stegen (GK), Semedo, Pique, Umtiti, Alba, Rakitic, Busquets, Arthur, Dembele, Messi, Coutinho